Debra Messing has filed for divorce from her husband of 11 years.
The Smash actress and Daniel Zelman announced their separation last year but continued to live together for the sake of their eight-year-old son, Roman.
However, Debra (43) has now decided to officially end their union and is citing "irreconcilable differences" as the reason behind the split.
According to gossip website TMZ.com, Debra is requesting joint custody of their son and is also seeking spousal and child support.
Messing — who has been linked to her Smash co-star Will Chase since the split — recently spoke about the breakdown of her marriage and insisted she had no regrets.
She said: "Twenty years. It's a very long time. I think the institute of marriage is a noble thing. The idea of a partner for life is incredibly romantic. But now we're living to 100. A hundred years ago people were dying at age 37. Til death do us part was a much different deal."
The couple met at New York University in the 1990s and tied the knot in September 2000.
Although they announced their split in December 2011, their date of separation is listed as 15 February 2010.